Plastic pollution and climate change have commonly been treated as two separate issues
and sometimes are even seen as competing. Here we present an alternative view that these …

Human activity in the deep sea is extending ever deeper, with recent research showing that
this environment is more sensitive to human and natural impacts than previously thought …

Background Patients with follicular lymphoma may survive for periods of less than 1 year to
more than 20 years after diagnosis. We used gene-expression profiles of tumor-biopsy …

Background Phosphatidylinositol-3-kinase delta (PI3Kδ) mediates B-cell receptor signaling
and microenvironmental support signals that promote the growth and survival of malignant B …

Abstract In 2006 the United Nations called on states to implement measures to prevent
significant adverse impacts to vulnerable marine ecosystems (VMEs) in the deep sea. It has …

The monocarboxylate transporter MCT4 mediates lactic acid efflux from most tissues that are
dependent on glycolysis for their ATP production. Here we demonstrate that expression of …

The B-cell receptor (BCR) is a key survival molecule for normal B cells and for most B-cell
malignancies. Recombinatorial and mutational patterns in the clonal immunoglobulin (Ig) of …

Over the last decades, population densities in coastal areas have strongly increased. At the
same time, many intertidal coastal ecosystems that provide valuable services in terms of …

Predictive habitat models are increasingly being used by conservationists, researchers and
governmental bodies to identify vulnerable ecosystems and species' distributions in areas …

Translocation of monocarboxylate transporters MCT1 and MCT4 to the plasma membrane
requires CD147 (basigin) with which they remain tightly associated. However, the …