False-response monitoring during automated perimetry

Optom Vis Sci. 1998 Jul;75(7):513-7. doi: 10.1097/00006324-199807000-00020.

Abstract

Purpose: To ascertain the accuracy and precision of the catch-trial monitor used to estimate the false-response rate in automated perimetry.

Methods: False responses were automatically injected at various rates by modified perimetric software while reliable perimetric subjects underwent visual field thresholding. Four repeat tests were conducted within a 1-hour period to quantify the variability and bias inherent in the catch-trial technique.

Results: The catch-trial method gave a very accurate estimate of the average false-response rate. Precision, however, was quite poor because of the small sample of catch trials. Outcomes were predicted using a binomial model, and we demonstrated good concordance between the model and empirical data. When the true false-response rate was 33%, estimates derived from catch trials ranged from 7 to 57%.

Conclusions: Although the catch-trial method gave an accurate estimate of the false-response rate, confidence intervals were too wide to provide a high level of precision. Our data suggest that tests with reported false-response rates < 20% may be considered reliable.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • False Negative Reactions
  • Humans
  • Male
  • Predictive Value of Tests
  • Reproducibility of Results
  • Visual Field Tests / standards*
  • Visual Fields*