Diagnostic index of four models with different test variables
| Sensitivity (%) | Specificity (%) | Youden index | Cut-off points | |
| Model A* | 48 | 68 | 0.289 | 4 |
| Model B† | 80 | 59 | 0.391 | 4 |
| Model C‡ | 80 | 55 | 0.345 | 4 |
| Model D§ | 88 | 55 | 0.425 | 4 |
Operative variables:
Each OCT characteristic: 1 point if present; otherwise, 0 point.
Aged ≥50 years: 1 point; aged <50 years: 0 point.
*The test variable is the total score of all ‘six OCT characteristics’.
†The test variable is the total score of ‘six OCT characteristics’ plus ‘hyper-reflective dots in the intraretinal layer and/or subretinal layer’.
‡The test variable is the total score of ‘six OCT characteristics’ plus ‘hyper-reflective dots in the intraretinal layer and/or subretinal layer’ and ‘female’.
§The test variable is the total score of ‘six OCT characteristics’ plus ‘hyper-reflective dots in the intraretinal layer and/or subretinal layer’, ‘female’ and “aged ≥50 years’.
Female, 1 point; male, 0 point.