Table 3

Reasons for antibiotic of choice. Logistic regression models predicting likelihood of choosing fluoroquinolone monotherapy and fortified vancomycin, correcting for location.

ReasonORp Value95% CI lower bound
Fluoroquinolone monotherapy
 Efficacy1.050.910.45 to 2.46
 Coverage0.300.020.11 to 0.81
 Availability20.86 <0.001*6.79 to 64.13
 Toxicity7.48 <0.001*2.53 to 22.09
 Synergy0.160.080.02 to 1.23
 Resistance0.390.080.13 to 1.11
Fortified vancomycin
 Efficacy1.960.060.97 to 3.92
 Coverage7.10 <0.001*2.44 to 20.61
 Availability0.20 <0.001*0.09 to 0.44
 Toxicity0.10 0.003*0.02 to 0.45
 Synergy0.750.560.29 to 1.95
 Resistance12.51 <0.001*4.97 to 31.45
  • *Statistically significant after Holm-Šídák correction for multiple comparisons.